Honda 250r Tuning problems need help??

[TRX-RACING]

Origionally the bike had a stock bore of 66mm but had a 38mm carb on it (stock 34mm) which was entirely to big, the bike didnt run right at all. So i got a new 35mm for it and it ran lean to long and blew up.............
So now i got it all back together it has a CT Racing full pipe on it, Stage 2 Pro National port and polish and 76mm wiseco piston. Im having big tuning problems.
1 to start off with, air/fuel mixture 1.5 turns out. 165 main, needle all the way up so it would run rich, simptoms were wet plug no power at all.
2-165 main 2nd notch from bottom, plug dry black no power all around.
3-160 main 2nd notch from bottom, plug brown black around the outsides, no low end, mid breaking up and top end breaking up.
4-160 main, needle in middle same simptoms as step 3
5-155 main Top excellent, mid excellent, and low great slugish take off. then i checked the plug and dont even want to talk about it, but melted the end off
Crank seals are brand new dont leak* The bike ran good as i went lower aka leaner WHY!!!! Step 5 road around once didnt take long!!!!! Could be out of time?* im begging you people ive tuned alot of 4 stokes ive never seen anything like it??? Could it be reeds, everything else is brand new. gas mixture is 40:1. Running NGK BR9ES plug

[R4ever]

i would try 158 main clip in the middle... what pilot u running?? i would throw in a 48 and put the air/fuel screw 2 turns out.. and see where that gets ya.. btw where u at and whats the elevation?

[TRX-RACING]

Originally Posted by R4ever

i would try 158 main clip in the middle... what pilot u running?? i would throw in a 48 and put the air/fuel screw 2 turns out.. and see where that gets ya.. btw where u at and whats the elevation?

Im running a 52 pilot. im in ohio. 155 extremely lean and 160 was acting to rich So ill try inbetween that. It might need to be a little lean? What to you think about the reeds? Thanks for the advice